Market Signal Report
BONUS: TPST, MEDS, RETO — Senlang CAR-T + Helomics (before the bell) ‌
MARKET SIGNAL REPORT
POWERED BY STOCKSTOTRADE
WED SEP 16  Premarket   SPY ▲0.32%   QQQ ▲0.63%   IWM ▲0.23%

Editor's Note: Larry Benedict — the hedge fund legend who beat the S&P 500 by 18 times in 2025 and made his clients $95 million during the 2008 crisis — says Trump's installation of a new Federal Reserve chair is triggering the most significant shift in U.S. markets in nearly 20 years. He has already identified the one ticker he believes will be at the center of the money flows — and he's revealing it completely free. Click here to see the details or read more below…


Dear Reader,

According to Wall Street Legend Larry Benedict, the greatest wealth-building event in nearly 20 years is coming.

Click here — Larry says you need to make this move now.

Larry has been trading around Fed moves for 40 years.

He's seen every major shift since the 1980s.

And he says he has never seen a setup this clear.

The last time the Fed made a shift this significant — 2022 — Larry went 11 for 11 on winning trades while the S&P lost nearly 20%.

One trade alone returned 117% in under a month.

He says what's coming now could be even bigger than that.

He's recorded a free briefing where he names the one ticker he believes will capture billions of dollars. Position correctly and you could see huge gains.

But you need to act now.

Click here to get Larry's ticker and his full briefing now.

Best wishes,

Lauren Wingfield
Managing Editor, The Opportunistic Trader

P.S. Larry says the “Trump Fed Takeover” is one of the biggest opportunities he's seen in his career. But to take advantage, you need go get positioned right now.

Get the full details here.

Fed day. SPY 759.82 (+0.32%), QQQ 708.95 (+0.63%), IWM 285.79 (+0.23%) on the premarket prints vs Tuesday's close. Mild green. Not a dump. Futures were steady into a 2pm ET FOMC decision with markets pricing roughly a 92% shot at +25bp under Chair Warsh. Soft bounce after Tuesday's red. The stock of the morning is TPST. Premarket prints, not the cash open.

24/7 Market News 07:37 ET: Tempest doubles down on in-vivo CAR-T with a second delivery platform — exclusive option on Senlang's CD7-targeted lentiviral work. Money Morning wrapped the same overnight rip on Sep 16. MT Newswire had TPST in Top Premarket Gainers at 07:12 ET. TPST last 1.06, +40.5%, volume ~19.9M on Nasdaq. That's the tape. Trade the wire.

Two more names with actual prints. MEDS last 3.59, +121.6%, ~42.0M. ACCESS Newswire 16:05 ET Sep 15: Helomics AI cancer diagnostics lab and CRO from Axe Compute for $1.5M. The Fly 16:10 ET. 24/7 Market News followed at 18:09 ET. RETO last 3.46, +23.6%, ~18.7M on Nasdaq. MT Newswire listed it in Top Premarket Gainers at 07:12 ET. No fresh catalyst on the wire this morning — continuation after Tuesday's rip. Three prints. If you don't have a wire, you don't have a trade. Skip empty percent.

THE HEADLINE THAT MATTERS TODAY

 

Tempest Doubles Down on In Vivo CAR-T with Second Delivery Platform

24/7 Market News via QuoteMedia | Sep 16, 2026 07:37 ET

TOP PRE-MARKET MOVERS

 

1 · TPST +40.5% — 1.06 | ~19.9M | Nasdaq. 24/7 Market News 07:37 ET: exclusive Senlang in-vivo CAR-T option; Money Morning Sep 16 wrap.

2 · MEDS +121.6% — 3.59 | ~42.0M | Nasdaq. ACCESS Newswire 16:05 ET Sep 15: Helomics AI cancer diagnostics + CRO from Axe Compute ($1.5M); The Fly 16:10 ET.

3 · RETO +23.6% — 3.46 | ~18.7M | Nasdaq. MT Newswire Top Premarket Gainers 07:12 ET. No fresh catalyst on the wire — continuation after Tue's rip.

What this crash trader is doing with oil while crude stays elevated (From Brownstone Research)

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SHH. THIS IS A CLUB.

You only get the morning tape because you actually open and click. Go quiet before the bell and we give your chair to someone who still reads the wires. No waitlist. No apology.

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Signal over noise. Fed day. TPST Senlang tape.